Intergumentary System

Integumentary System Laszlo Vass, Ed. D. Version 42-0280-00-01 Lab Report Assistant This document is not meant to be a substitute for a formal laboratory report. The Lab Report Assistant is simply a summary of the experiment’s questions, diagrams if needed, and data tables that should be addressed in a formal lab report. The intent is to facilitate students’ writing of lab reports by providing this information in an editable file which can be sent to an instructor. Purpose: What is the purpose of this exercise? The purpose of this exercise in to learn about structures and functions of the skin.Is there any safety concerns associated with this exercise? If so, list what they are and what precautions should be taken. As always take precautions when handling the microscope and slides and always have a clean safe work area. Exercise 1: Structures of the Skin Observations Before beginning, set up a data table similar to this Data Table 1. Fill in the names of the numbered st ructures. Skin Diagram (National Library of Medicine at http://nih. nlm. gov) Data Table 1: Structures of Skin| Item| Name| 1. | Hair shaft | 2. | Arrector pili muscle | 3. Sebaceous gland | 4. | Hair follicle | 5. | Sweat gland | 6. | Pacinian corpuscle | 7. | Subcutis (hypodermis) | 8. | Dermis | 9. | Epidermis | 10. | Sensory nerve ending | 11. | Dermal papilla | 12. | Sweat pore | Questions A. How does the skin tan when exposed to ultraviolet light? When ultraviolet light penetrates skin it begins to break down DNA causing the body to produce melanin. The melanin makes the body become darker or tanner and when the body is darker the more protected it is from the sun and sunburn. B. Describe the functions of the epidermis.The epidermis is the outermost layer that has keratinized squamous epithelium and the dermis. The epidermis has a bunch of different cells which allow it to perform many different functions. The keratinocytes produce keratin that produce fibrous protein that giv es skin protective properties while the melanocytes produce melanin to protect deeper cells from ultraviolet radiation and allows the skin to tan. Merkel cells from sensitive touch receptors on nerve endings and langerhans’ cells are involved in the immune response of the skin. Stratum basale constantly go through cell division to produce million of new skin daily. Stratum spinosum has think bundles of protein and stratum granulosum contain lipids that provide waterproofing for the skin. The stratum lucidum is a layer of flattened keratinocytes are only found in thick skin. Stratum corneum is the outer layer of the epidermis made of squished and flattened layers of dead keratinocytes. C. Describe the functions of the sweat glands. Sweat glands are controlled by sympathetic nervous system and regulate body temperature.When the body becomes to hot they secrete water to the skin surface and the heat is removed by evaporation. D. Compare the structure of the epidermis to that of the dermis. The epidermis consists of several different types of cells while the dermis canonists of dense, irregular connective tissue. E. Fill in the following table by either inserting the name of the structure/cell or by giving its function(s): Structure/Cell| Function(s)| melanocytes| Makes a pigment for tanning| Langerhans cells| Small and involved in the immune response| Merkel cells | Found on nerve endings|Stratum lucidum| Provides protection, thick found of palms a soles makes skin waterproof | Reticular layer | The blood supply here provides radiational cooling for the body| Exercise 2: Microscopic Structure of the Skin Observations Sketch and label your keratinized stratified squamous epithelium slide in the space below. Be sure to label all of the structures in the epidermis and dermis you were able to find: Questions A. Compare your slide to the photomicrograph example in the lab Procedure. How are they the same and how are they different?Propose a reason why you would see several differences between different slides of skin. B. What is keratin? Is fibrous protein that gives the skin its protective properties? C. Why is skin keratinized? Keratinized cells give skin a tough protective barrier. After a cell is born it begins to make protein called keratin that they store inside them. As the cells grow they build up with this protein until their so full they die forming a tough layer of packets of keratin. Exercise 3: Clinical Conditions of the Skin Questions A. What are the three types of skin cancer?Squamous cell carcinoma, basal cell carcinoma, and melanoma B. Which type of skin cancer is easily treatable? Basal cell carcinoma C. Explain why melanoma is so dangerous. Melanoma can spread to other areas of the body. D. What factors can cause acne? Acne is caused when sebum isn’t able to pass through the hair follicle. This causes cells from the lining of the follicle to shed to fast and clump together clogging up the follicle’s openi ng so sebum cannot get through. E. What is a common myth about the cause of acne?Eating chocolate, greasy food or dirty skin F. What are some treatments for acne? Dermatologists use a medication that reduces clumps of cells in the follicles, oil production, bacteria, and inflammation. Depending on the case of the acne the doctor may prescribe a topical medication or an oral medication. G. Describe the signs of first, second and third degree burns. First- affects only the outer layer, epidermis. Second- damage the epidermis and the dermis Third- involve damage or complete destruction to the fullest depth of the skin and underlying tissue. H. What are the principle effects of aging on the skin?